43 to 3.19, indicating increased stroke risk associated with obesity, however it was measured, even after adjustment for potential confounders. Additional adjustment for factors that may mediate the relationship, such as diabetes and hypertension, significantly attenuated the associations, suggesting that these factors may explain much of the stroke risk associated with obesity.\n\nConclusions-Degree of obesity, defined by body mass index, waist circumference, or waist-to-hip ratio, was a significant risk factor for ischemic stroke regardless of
sex or race. (Stroke. 2010;41:417-425.)”
“Background and objectives: The kidney is important not only in the genesis of blood pressure elevation, but declining renal function is also important for predicting cardiovascular risk. The primacy of the kidney in causing essential hypertension was a topic of Nutlin-3 price debate until the proof-of-principle experiment was performed, which demonstrated remission of essential hypertension in six African-American hypertensives with ESRD after they received successful kidney transplants from normotensive donors. The resolution of hypertension and hypokalemia in a patient with
Liddle’s syndrome and ESRD after subsequent successful renal transplantation also demonstrated the primacy of the kidney in a monogenic form of hypertension related to sodium epithelial channel dysfunction.\n\nDesign, setting, MK2206 participants, & measurements: A review of the available evidence linking cardiovascular disease with chronic kidney disease.\n\nResults: The cause for the inverse continuous relationship between kidney function and cardiovascular
events in patients with native kidney disease and kidney transplant recipients is unknown but may be related to traditional and nontraditional HDAC assay cardiovascular risk factors. This is an important clinical concern and requires close attention to cardiovascular risk reduction measures.\n\nConclusions: Increased cardiovascular disease in patients with chronic kidney disease is an important clinical concern. Improved biomeasures of cardiovascular risk and response to therapy are needed. Clin I Am Soc Nephrol 4 2045-2050, 2009 doi 10 2215/CJN 03050509″
“Remote Magnetic Navigation for VT Ablation. Background: This study aimed to compare acute and late outcomes of VT ablation using the magnetic navigation system (MNS) to manual techniques (MAN) in patients with (SHD) and without (NSHD) structural heart disease. Methods: Ablation data of 113 consecutive patients (43 SHD, 70 NSHD) with ventricular tachycardia treated with catheter ablation at our center were analyzed. Success rate, complications, procedure, fluoroscopy, and ablation times, and recurrence rates were systematically recorded for all patients. Results: A total of 72 patients were included in the MNS group and 41 patients were included in the MAN group. Patient age, gender, and right ventricular and left ventricular VT were equally distributed.