The RD of sickness absence due to CMDs was 84.5 per 1,000 person-years. We distinguished recurrent sickness absence due to the same CMD and recurrent absence due to other CMDs. Because both could apply to the same employee, the total recurrence is not equal to the sum of recurrence due to the same disorder and recurrence due to other disorders. Table 4 Recurrence density (95% {Selleck Anti-cancer Compound Library|Selleck Anticancer Compound Library|Selleck Anti-cancer Compound Library|Selleck Anticancer Compound Library|Selleckchem Anti-cancer Compound Library|Selleckchem Anticancer Compound Library|Selleckchem Anti-cancer Compound Library|Selleckchem Anticancer Compound Library|Anti-cancer Compound Library|Anticancer Compound Library|Anti-cancer Compound Library|Anticancer Compound Library|Anti-cancer Compound Library|Anticancer Compound Library|Anti-cancer Compound Library|Anticancer Compound Library|Anti-cancer Compound Library|Anticancer Compound Library|Anti-cancer Compound Library|Anticancer Compound Library|Anti-cancer Compound Library|Anticancer Compound Library|Anti-cancer Compound Library|Anticancer Compound Library|Anti-cancer Compound Library|Anticancer Compound Library|buy Anti-cancer Compound Library|Anti-cancer Compound Library ic50|Anti-cancer Compound Library price|Anti-cancer Compound Library cost|Anti-cancer Compound Library solubility dmso|Anti-cancer Compound Library purchase|Anti-cancer Compound Library manufacturer|Anti-cancer Compound Library research buy|Anti-cancer Compound Library order|Anti-cancer Compound Library mouse|Anti-cancer Compound Library chemical structure|Anti-cancer Compound Library mw|Anti-cancer Compound Library molecular weight|Anti-cancer Compound Library datasheet|Anti-cancer Compound Library supplier|Anti-cancer Compound Library in vitro|Anti-cancer Compound Library cell line|Anti-cancer Compound Library concentration|Anti-cancer Compound Library nmr|Anti-cancer Compound Library in vivo|Anti-cancer Compound Library clinical trial|Anti-cancer Compound Library cell assay|Anti-cancer Compound Library screening|Anti-cancer Compound Library high throughput|buy Anticancer Compound Library|Anticancer Compound Library ic50|Anticancer Compound Library price|Anticancer Compound Library cost|Anticancer Compound Library solubility dmso|Anticancer Compound Library purchase|Anticancer Compound Library manufacturer|Anticancer Compound Library research buy|Anticancer Compound Library order|Anticancer Compound Library chemical structure|Anticancer Compound Library datasheet|Anticancer Compound Library supplier|Anticancer Compound Library in vitro|Anticancer Compound Library cell line|Anticancer Compound Library concentration|Anticancer Compound Library clinical trial|Anticancer Compound Library cell assay|Anticancer Compound Library screening|Anticancer Compound Library high throughput|Anti-cancer Compound high throughput screening| Confidence Interval) of sickness absence due to CMDs, stratified according to initial diagnosis Initial episode disorder N Years at risk Recurrent CMD sickness absence
same mental disorder Recurrent CMD sickness absence other mental disorder Recurrent CMD sickness absence total Distress symptoms 3,448 8,269 44.0 (39.5–48.5) 48.0 (43.3–52.7) Torin 2 order selleck chemical 79.5 (73.4–85.5) Adjustment disorder 4,228 9,267 49.7 (45.2–54.3) 45.0 (40.7–49.3) 84.1 (78.2–90.0) Depressive symptoms 751 1,833 43.6 (34.1–53.2) 68.7 (56.7–80.7) 94.9 (80.8–109.0) Anxiety symptoms 325 765 37.9 (24.1–51.7) 56.2 (39.4–73.0) 81.0 (60.9–101.2) Other psychiatric disorders 1,152 2,646 41.2 (33.5–48.9) 67.7 (57.7–77.6) 95.6 (83.8–107.4) Total 9,904 22,779 45.8 (43.0–48.6) 51.0 (48.1–53.9) 84.5
(80.7–88.3) Sickness absence due depressive symptoms had the highest risk of recurrence. The RD of sickness absence due to distress symptoms, adjustment disorders and anxiety was also high. Determinants of recurrent sickness absence due to CMDs The RD among men was almost as high as among women: 82.7 (95 CI = 77.9–87.5) per 1,000 person-years in men and 87.3 (95% CI = 81.2–93.4) per 1,000 person-years in women. The recurrence risk for men did not differ from the recurrence risk for women, after adjustment for type of mental disorder, age, salary scale, full-time or part-time work, tenure and company.
In order to assess effect modification by gender, we stratified the Amylase multivariate analysis according to gender (Table 5). In men, depressive symptoms were related to higher recurrence of sickness absence due to CMDs than distress symptoms and adjustment disorders. In women, no difference by diagnostic category was found. Men between 45 and 55 years of age and women under 45 had a higher risk of recurrent sickness absence due to CMDs than those in the age group of ≥55 years. Men and women with a lower salary had a higher risk of recurrent sickness absence due to CMDs than those with a higher salary, after adjustment for all other variables. Married women had a higher risk of recurrent sickness absence due to CMDs than unmarried women. We found no difference in the risk according to marital status in men.