Opdam et al. [30] reported that a Cox regression analysis revealed a significant increase in the failure rate of the posterior resin composite restorations for high caries risk patients. Aoyama et al. [31] indicated BMS-907351 mw that the longevity of restorations placed in posterior teeth was associated with the occlusal status, that is, the longevity was significantly

shorter in patients with Eichner Indices B1, B2 and B3 compared to those with Index A. In our study [33], retreatment risk was objectively rated based on a clinical history referring to a previous report [42]: low (no restorations in the last 3 years), medium (one or two restorations in last 3 years) and high (three or more restorations in last 3 years). In addition, the retreatment risk was assumed to be constant from the beginning. There were significant differences in survival curves between high risk and others as shown in Fig. 1. Experience may have an influence on skill and criteria for replacement [36], [37] and [39]. The influence of experience on the longevity of resin composite restorations was studied in three selected articles and our study [27], [29], [30] and [32]. No consistent results were found even in similar studies [29] and [30]. The influence of experience varied between restorative techniques. These are probably because of the small numbers 3-deazaneplanocin A of operators. Another possible factor

is the year while the operators in their dental schools since the material and technology in restorative dentistry

have considerably changed during recent years. It has been speculated that the operator’s skill has a great effect on the longevity of restorations, and there seems to be no disagreement about this speculation. However, few clinical studies have been performed to verify this hypothesis [43]. In our study [33], there was a significant difference in 10-year survival rates between the author and the other 24 dentists (Fig. 2). However, Cox proportional hazards model indicated no significant effects of experience or specialty (research fields and departments) on the survival function among 24 dentists. Criteria for replacement Phosphatidylinositol diacylglycerol-lyase may have some effect on the longevity of resin composite restorations [9] and [29], as suggested by Browning and Dennison [34]. Unfortunately, standardized diagnostic criteria for replacement of restorations have not established yet. Although it is relatively easy to obtain agreement from each operator in the case of pulpitis, retention failure and fracture of restorations, it is more difficult to obtain agreement on secondary caries, marginal discoloration, moderate color mismatching, and composite wear [1] and [40]. Hawthorne and Smales [27] indicated that a change of dentist had no significant effect on restoration survival except for except resin composite restorations in which the change tended to show a positive effect.