The variables associated with the non-response were the same in the intervention and control group. Reasons for non-response were not completing a questionnaire at each measurement, not being able to match the

questionnaire to a questionnaire completed in previous measurements, refusal to provide home address or wrong or unknown home address, and missing data on the primary outcome measure. The intervention group more often had a Christian religion, more often had parents with a higher education level, and more often attended a higher level secondary school than the control group (Table 1). There were no significant differences between the two groups Selleckchem CHIR99021 in baseline behavioral determinants of smoking. Additional analyses showed that at baseline paternal smoking was significantly more prevalent in the control condition and smoking by the teacher in the intervention condition (however, smoking by the teacher did not differ between groups in the following school years). The analyses were adjusted for these differences. At baseline smoking was more often allowed and lessons on smoking were less often provided in the intervention schools. In secondary school, intervention students more often Onalespib mouse reported that their parents promised them a reward if they did not start smoking and the

control students more often reported having had lessons on smoking that year (Table 2). In total 47% of students in the intervention group received all activities in 5th grade and 31% received all activities

in 6th grade. The activity that was less often provided was planning how to react to social pressure towards smoking. After first the lessons in fifth grade, intervention students perceived more short-term and long-term disadvantages of smoking than control students. The control group perceived fewer advantages than the intervention group. Next, the students in the intervention group more often expected that their nuclear social network did not smoke and that their network would not approve if they would smoke. The significant effects found after the lessons in fifth grade disappeared in sixth grade. After the lessons in fifth and sixth grade, the intervention group still perceived more advantages of smoking than the control group. There were no significant differences on the other determinants of smoking behavior (Table 3 and Table 4). In secondary school in particular, social pressure to smoke and perceived prevalence of smoking in the diffuse and nuclear network increased in both the intervention and the control group. These social influence determinants increased, however, significantly less in the intervention group. The intervention group had also more positive attitudes towards non-smoking, had a higher intention not to smoke, and smoked less often than the control group (Table 3 and Table 4).