Overall, these data suggest that patients with unilateral

PWD may, in fact, have a deficit in (left lateralized) temporal processing ability, however they also show that a rapid temporal processing deficit is, by itself, unable to account for this patient’s JNJ-64619178 order speech perception deficit. (C) 2010 Elsevier Ltd. All rights reserved.”
“This study explores whether brain polarization could be effective in modulating multisensory audiovisual interactions in the human brain, as measured by the ‘sound-induced flash illusion’ (Shams et al., 2000). In different sessions, healthy participants performed the task while receiving anodal, cathodal, or sham tDCS (2 mA, 8 min) to the occipital, temporal, or posterior parietal cortices. We found that up- or down-regulating cortical excitability by tDCS can facilitate or reduce audiovisual illusions, depending on the current polarity, the targeted area, and the illusory percept. Specifically, the perceptual ‘fission’ of a single flash, due to multiple beeps, was increased after anodal tDCS of the temporal cortex, and decreased after anodal stimulation of the occipital cortex. A reversal of such effects was induced by cathodal tDCS. Conversely, the perceptual ‘fusion’ of multiple flashes due to a single beep was unaffected by tDCS. This evidence adds novel clues on the cortical substrate of the generation Dorsomorphin ic50 of the sound-flash illusion, and opens new attractive possibilities

for modulating multisensory perception in humans: tDCS appears to be an effective A-1331852 manufacturer tool to modulate the conscious visual experience associated with multisensory interactions, by noninvasively shifting cortical excitability within occipital or temporal

areas. (C) 2010 Elsevier Ltd. All rights reserved.”
“In patients with right brain damage and left visual neglect, attention tends to be captured by right-sided objects and cannot easily disengage from them. While these phenomena can account for several clinical and experimental patterns of performance such as biased visual search, its role is more controversial for other neglect-related signs, such as the typical rightward shifts in horizontal line bisection. It is thus important to see whether and how attentional orienting can bias line bisection in normal participants using standard clinical bisection stimuli. In 3 experiments, we explored the Attentional Repulsion Effect (ARE, Suzuki & Cavanagh, 1997) on pre-bisected lines. Normal observers saw horizontal lines with a vertical bisection mark near the center, preceded by a cue to the left or right of the line, or by no cue. On each trial, observers indicated whether they saw the bisection mark to the left or at the right of the midpoint. We plotted the proportion of ‘seen-at-right’ responses as a function of the mark’s actual position. For uncued lines, the point of subjective equality was slightly at the left of the true center, consistent with the pseudoneglect phenomenon.