Authors’ contributions JMC was the primary investigator,

designed the study, obtained grant funds, supervised subject recruitment, data acquisition, data specimen collection, and manuscript IWR-1 preparation. MWR, RG, and HJ performed data specimen analysis. JMC was primarily responsible for writing the manuscript. TM, RW, SASC, and VP made substantial contributions to manuscript writing and preparation. All authors read and approved the final manuscript.”
“Erratum to: Osteoporos Int (2006) 17: 426—432 DOI 10.1007/s00198-005-0003-z Owing to a technical error, a number of non-vertebral fractures had not been included in the database. Owing to changes in the Milciclib clinical trial informed consents for some of the participants, at the time of repeated analyses, the study cohort changed from 27,159 to 26,905 participants. A total of 1,882 non-vertebral fractures (not 1,249 as stated in the publication) were registered. After excluding all subjects with missed measurements of any metabolic syndrome criteria (n = 152), 750 men and 1108 women (not 438 men and

789 women as stated in the publication) suffered non-vertebral fractures. The risk estimates of the associations between having three or more of the metabolic syndrome criteria and non-vertebral fractures Pifithrin �� and changed to (RR 0.81, 95% CI 0.64–1.04) in men and (RR 0.78, 95% CI 0.65–0.93) in women. The trend towards reduced fracture risk by increasing mean BP in men was no longer significant

(Fig. 2). We apologize for any inconvenience caused by this unfortunate error.”
“Background MRI plays a key role in the preclinical development of new drugs, diagnostics and their delivery systems. However, very high installation and running cost of existing superconducting MRI machines limit the spread of the method. The new method of Benchtop-MRI (BT-MRI) has the potential to overcome this limitation due to much lower installation and almost no running costs. The lower quality of the NMR images is expected due to the low field strength and decreased magnet homogeneity. However, very recently we could show that BT-MRI is able to characterize floating Dapagliflozin mono- or bilayer tablets, osmotic controlled push-pull tablets [1–4] or scaffolds for tissue engineering in vitro [5]. A broad, important and increasing range of MRI applications are linked with preclinical studies on small rodents such as mice or rats [6–8]. Thereby, first developments and testing of more compact MRI systems have been reported [9, 10]. In the present study we have tested a prototype of a new in vivo BT-MRI apparatus. Clearly, BT-MRI could overcome one of the current main limitations of preclinical MRI, the high costs. However, the question arises, whether BT-MRI can achieve sufficient image quality to provide useful information for preclinical in vivo studies.