2003). Douglas et al. hypothesized that CCT findings may predict the short-term risk of stroke during a follow-up period of 90 days after a TIA. The impact of CCT findings on the early short-term risk of stroke after a TIA has not been previously investigated. However, data on the use of CCT in patients with a TIA are also lacking. The aims of the present study are to determine the frequency of detection of a new infarct

by noncontrast CCT in patients with a TIA who present to hospital within 48 h of symptom onset, to evaluate the independent predictors of infarct detection, and to investigate the association between the presence of a new infarct and the short-term risk of stroke Inhibitors,research,lifescience,medical during hospitalization. Methods Patients and design During a 36-month period (beginning Inhibitors,research,lifescience,medical November 2007), 1533 consecutive patients (mean age, 75.3 ± 11 years; 54% female; mean National Institutes of Health Stroke Scale [NIHSS] score 1.7 ± 2.9; median, 1; interquartile range, 2–5) who were suffering from a TIA and were admitted to the hospital within 48 h of symptom onset and underwent CCT as a diagnostic evaluation of etiology were enrolled in our prospective study as part of a benchmarking project. Of the 15 participating sites, two were university departments of neurology, eight were departments of neurology at nonuniversity hospitals, and five

Inhibitors,research,lifescience,medical were departments of internal medicine at nonuniversity hospitals. A stroke unit was present in 10 of these hospitals. Inhibitors,research,lifescience,medical All patients provided written informed consents for their {Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleck Anti-infection Compound Library|Selleck Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Selleckchem Anti-infection Compound Library|Selleckchem Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|Anti-infection Compound Library|Antiinfection Compound Library|buy Anti-infection Compound Library|Anti-infection Compound Library ic50|Anti-infection Compound Library price|Anti-infection Compound Library cost|Anti-infection Compound Library solubility dmso|Anti-infection Compound Library purchase|Anti-infection Compound Library manufacturer|Anti-infection Compound Library research buy|Anti-infection Compound Library order|Anti-infection Compound Library mouse|Anti-infection Compound Library chemical structure|Anti-infection Compound Library mw|Anti-infection Compound Library molecular weight|Anti-infection Compound Library datasheet|Anti-infection Compound Library supplier|Anti-infection Compound Library in vitro|Anti-infection Compound Library cell line|Anti-infection Compound Library concentration|Anti-infection Compound Library nmr|Anti-infection Compound Library in vivo|Anti-infection Compound Library clinical trial|Anti-infection Compound Library cell assay|Anti-infection Compound Library screening|Anti-infection Compound Library high throughput|buy Antiinfection Compound Library|Antiinfection Compound Library ic50|Antiinfection Compound Library price|Antiinfection Compound Library cost|Antiinfection Compound Library solubility dmso|Antiinfection Compound Library purchase|Antiinfection Compound Library manufacturer|Antiinfection Compound Library research buy|Antiinfection Compound Library order|Antiinfection Compound Library chemical structure|Antiinfection Compound Library datasheet|Antiinfection Compound Library supplier|Antiinfection Compound Library in vitro|Antiinfection Compound Library cell line|Antiinfection Compound Library concentration|Antiinfection Compound Library clinical trial|Antiinfection Compound Library cell assay|Antiinfection Compound Library screening|Antiinfection Compound Library high throughput|Anti-infection Compound high throughput screening| inclusion in this prospective study. Patients who met the following criteria were included in this study: patients with a TIA (in accordance with the definition that was put forth by the World Health Organization) with symptom lasting less than Inhibitors,research,lifescience,medical 24 h, patients who were admitted to the hospital within the first 48 h of symptom onset. The exclusion criteria were an admission to hospital after 48 h of symptom onset, a possible seizure, a history of migraine, and age less than 18 years. The documentation and data collection procedures followed a uniform study manual. Baseline

characterizations at admission (Table 1)—gender, age, NIHSS score at admission, duration of symptoms, time to assessment, symptoms of TIA, vascular risk factors, and previous history those of stroke—were documented and analyzed. The evidence of a new infarct that was related to the presenting symptoms was abstracted from CCT findings in patients’ radiology reports. The CT scans were read by neuroradiologists who were not involved in the study. Table 1 Baseline characteristics of patients with TIA and factors associated with evidence of a new infarct1 The CCT was part of the routine diagnostic evaluation of etiology of the stroke-related neurological symptoms in patients presenting with symptoms of cerebrovascular disease including TIA.