Results: Patients who attended the IBD clinic were at different stages of the disease activity and many were recent inpatients. The dietitian assessed 26 patients for which majority had Crohn’s disease (20/26), with male dominance (14/26) and a median age of 35 years (range 16–71 years). 50% of patients were malnourished using the SGA (Table 1), and
21 (81%) had lost weight prior to clinic review (Table 2) with an average weight loss of Obeticholic Acid clinical trial 10% usual body weight. Table 1 SNAQ screening tool and SGA assessment tool results Table 2 Weight loss in patients Conclusion: Malnutrition and weight loss frequently occurs in patients at all stages of IBD suggesting a role for dietary advice in outpatient clinics. Screening tools such as SNAQ may identify patients at risk of malnutrition, which can be determined through multifaceted assessments, to allow provision of specific advice. 1. Neelemaat F, Kruizenga HM, de Vet HCW, Seidell JC, Butterman M, van Bokhost-de van der Schueren MAE 2008 Screening malnutrition Small molecule library ic50 in hospital outpatients. Can the SNAQ malnutrition screening tool also be applied to this population? Clinical Nutrition 27, 439e446 2. Detsky AS, McLaughlin JR, Baker JP, Johnston N, Whittaker S, Mendelson RA, Jeejeebhoy KN What is subjective global assessment of nutritional status? Journal of Parenteral
and Enteral Nutrition 11:1:8–13 E STREBE,1 M DEETLEFS,2 G WITTE,1 H VAN WESTEROP,3 J KERSTEN,3 S HOUGEE1 1Nutricia Advanced Medical Nutrition, The Netherlands, 2Nutricia Advanced Medical Nutrition, Australia & New Zealand, 3TNO Triskelion BV, Zeist, Netherlands Introduction: According to some studies, enteral
nutrition (EN) seems to contain high fructan levels 1. This present study aims to demonstrate that the method used for analyses in these studies overestimates the fructan levels in EN. Methods: Nutrison 1.0, Nutrison 1.0 Multifibre (MF) and maltodextrin (MD, the main carbohydrate in EN not containing fructans) were analysed for fructan content. A similar enzymatic treatment was followed by (1) spectrophotometric analyses of glucose + fructose according to a commercially available FRUC-HK kit as previously used1 or (2) fructose analyses by High Performance Anion Exchange Chromatography with Pulsed Amperometric Detection (HPAEC-PAD)2. medchemexpress Measurements were conducted by Danone Research and were verified by TNO Triskelion, an independent contract research organization for food analysis. Results: Fructan content measurements (g/100 g) Danone Research TNO Triskelion Nutrison 1.0 Nutrison MF 1.0 MD Nutrison 1.0 Nutrison MF 1.0 MD FRUC-HK kit 1.6 2.1 >5 1.4 2.1 4.9 HPAEC-PAD (nd = not detected) <0.1 (nd) 0.59 <0.1 (nd) <0.1 (nd) 0.6 <0.1 (nd) FRUC-HK detected fructans with both Nutrison samples and MD. HPAEC-PAD confirms that Nutrison 1.0 and MD do not contain fructans and Nutrison MF contains fructans but at lower levels than indicated by FRUC-HK.